Staff

LAGADIC Laurent

Scientist Theme(s) : Phone: +33 2 23 48 52 37 Email : laurent.lagadic@inrae.fr Address: UMR DECOD, 65 rue de Saint-Brieuc Bât. 19, CS 84215, 35042 Rennes Cedex, France Keywords: Aquatic ecotoxicology, Invertebrates, Pesticides, Biocides, Endocrine disruptors, Biochemical toxicology, Enzymology, Biomarkers, Reprotoxicity, Mesocosms

Expertise

• Aquatic Ecotoxicology, Ecotoxicity testing, Field and semi-field (mesocosm) ecotoxicological studies
• Biochemistry, Enzymology, Ecophysiology, Population dynamics
• Scientific group and project management
• International expertise in aquatic risk assessment of plant protection products and biocides

Current Position

• Research Director at INRA
• President of SETAC-Europe

Research

Current Research Topics

Biochemical and physiological changes induced by plant protection products and biocides in aquatic invertebrates and their consequences on individual reproductive performances and population dynamics. Endocrine-disrupting effects of pesticides and interactive effects of toxicant mixtures on aquatic invertebrates.

Current Collaborations

U3E INRA, Rennes [FR]
UMR INRA-Université de Chambéry CARRTEL, Thonon-les –Bains [FR]
CBS-INSERM-Université de Montpellier 1 [FR]
LEHNA, ENTPE-INRA, Lyon [FR]
LERES EHESP, Rennes [FR] IMBE, University of Aix-Marseille [FR]
IRCM-INSERM-Université de Montpellier 1 [FR]
LBBE, University Claude Bernard Lyon 1 [FR]
RCIM, University of Angers [FR]
LEMA, University of Le Havre [FR]
DYNECAR, University of Antilles and French Guyana
LEAE, University of Liège [BE]
University of Southern Denmark [DK]
University of Plymouth [UK]
Goethe University Francfurt-am-Main [GE]
EID-Atlantique [FR]
Total S.A. [FR]
ASCONIT Consultants [FR]
L’Oréal [FR]
CTIS BASF [GE]

Current projects

Consulting Experience

• Committee for the Surveillance of Mosquito Control Practices, Préfecture du Morbihan, Vannes (since 1998)
• Scientific and Technical Committee of the Etablissement Interdépartemental pour la Démoustication (EID) du littoral Atlantique (since 2009)
• President of the Expert Group “Insecticides for Vector Control”, Anses, France (2009-2012)
• Scientific and Technical Committee of the Centre of Resources and Scientific Expertise on Water in Brittany (CRESEB) (since 2010)
• Technical Committee of the French National Centre of Expertise on Vectors (CNEV), Montpellier, France (since 2010)
• Scientific Advisory Committee of French National Programme in Environment and Occupational Health, ANSES, France (since 2010)
• European Expert Group on Mollusc Reprotoxicity Testing, in connection to the OECD Validation Management Group for Ecotoxicity Testing (VMG-Eco 8) and the OECD Invertebrate Testing Expert Group (since 2010). OCDE
• Scientific Council of the INRA Research Centre of Rennes (Elected in 2011)

Teaching Experience

• Ecotoxicology module, Agrocampus Ouest, Rennes, France
• Master Environment Toxicologie, University of Angers, France
• Master ECOTROP, UEP Pollution et Ecosystèmes Continentaux, University of Antilles-Guyane, Pointe-à-Pitre, France
• Plant Protection and Environment Spec. , 3rd year of the "Cursus Ingénieur", AgroParisTech
• Professional Training Course: Police de l'eau appliquée aux contrôles des pollutions diffuses. Pesticide modules. ONEMA, Centre de Formation du Paraclet

M.Sc. and Ph.D. Supervision

M.Sc. Students

Fanny Caupos (Jan. – June 2012). Mesures d’activités enzymatiques de détoxication potentiellement utilisables comme biomarqueurs chez Macrobrachium rosenbergii (Crustacé, Décapode) exposé à la chlordécone en laboratoire. Master 2 Approches Intégrées des Ecosystèmes Littoraux, Université de La Rochelle. Co-supervisor: Soazig Lemoine (Université des Antilles et de la Guyane, Pointe-à-Pitre).

Chirine Hajlaoui (Jan. – June 2012). Etude des effets neurotoxiques de la chlordécone chez les arthropodes. Master 2 Altérations des Systèmes Biologiques, parcours Recherche, Université d’Angers. Co-supervisor: Bruno Lapied (Université d’Angers).

Ph.D. Students

Claire Duchet (Apr. 2005 – Oct. 2010). Evaluation du risque environnemental lié à l’utilisation de larvicides d’origine biologique dans le cadre de la lutte anti-culicidés. Développement et validation expérimentale de méthodes de suivi des effets a différents niveaux d’organisation biologique chez Daphnia pulex et Daphnia magna. PhD Thesis Agrocampus Ouest, Doctoral School Vie-Agro-Santé, 29 october 2010. Co-supervisor: Evelyne Franquet (IMBE, University Aix-Marseille).

Anthony Bouétard (Dec. 2009 – Apr. 2013). Potentiel évolutif des réponses moléculaires de défense vis-à-vis du stress chimique : étude chez Lymnaea stagnalis exposée à des pesticides. PhD Thesis Agrocampus Ouest, Doctoral School Vie-Agro-Santé. Co-supervisor: Marie-Agnès Coutellec.

Alpar Barsi (Feb. 2011 – present). Mechanistic Modelling of Reprotoxic Effects of Pesticides in the freshwater snail Lymnaea stagnalis (Molluscs, Gastropods). Funding: Marie-Curie Fellowship, ITN CREAM (http://cream-itn.eu/). INRA - Vrije Universiteit Amsterdam. Co-supervisor: Virginie Ducrot.

Fanny Caupos (March 2013 – present). Utilisation de Macrobrachium sp. comme organisme-sentinelle pour l’évaluation des variations spatio-temporelles de la pression chimique globale des rivières de Guadeloupe et de Martinique. Funding: CIFRE ASCONIT Consultants - INRA. PhD Thesis Agrocampus Ouest, Doctoral School Vie-Agro-Santé.

Ph.D. Students